This unusual story takes place in Kunugigaoka’s middle school. Korosensei is a strange creature with tentacles and a round and yellow head, capable of moving at Mach 20 and gifted with phenomenal force. This out of the ordinary professor teaches to the 3-E class (E like End) with the assumed goal of destroying the Earth next March. His students, a bunch of dunces with the particularity of being budding assassins, will try to assassinate their teacher in time to save the planet. So, are you ready to follow their very intense school year?